Editorial Commentary:Association of Mannose‐Binding Lectin Deficiency with Cryptosporidiosis
نویسندگان
چکیده
منابع مشابه
Immune Deficiency and Cryptosporidiosis in Rats
This study was intended to establish whether there is any relation between immune deficiency and cryptosporidiosis by using an animal model. Forty Rattus norvegicus rats obtained from the Experimental Animal Laboratories of the Ege University Faculty of Medicine were divided into two groups. The first group (n = 20) received corticosteroids (dexamethasone, 1.5 mg, subcutaneously, twice weekly) ...
متن کاملClinical manifestations of mannan-binding lectin deficiency.
Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system. Ongoing research attempt to illuminate at which conditions MBL deficiency m...
متن کاملmannose-binding lectin deficiency in patients with a history of recurrent infections
mannose-binding lectin (mbl) is a protein of innate immune system that is involved in opsonization and complement activation. mbl deficiency is associated with predisposition to infectious diseases; however subnormal levels are also seen in healthy subjects. the aim of this study was to investigate the prevalence and clinical manifestation of mbl deficiency in patients with increased susceptibi...
متن کاملinvestigation of mannose–binding lectin level and deficiency in patients with dermatophytosis
background dermatophytosis is a cutaneous fungal infection with a worldwide occurrence. in dermatophyte infections, the release of keratinocyte cytokines, in the presence of dermatophyte antigens, causes an acute phase response; subsequently, the acute-phase proteins are produced by hepatocytes. mannose–binding lectin (mbl), an acute-phase protein, also acts as a kind of pattern recognition rec...
متن کاملMannan binding lectin deficiency and concomitant immunodefects.
OBJECTIVE To determine the prevalence of a mannan binding lectin (MBL) deficiency in children with increased susceptibility to infections and to investigate whether other coexisting immunodeficiencies affecting opsonisation are needed to render MBL deficiency clinically significant. PATIENTS AND METHODS 343 serum samples were collected from 266 children with repeated infections, a single epis...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2006
ISSN: 1058-4838,1537-6591
DOI: 10.1086/505401